Nerve-blocking Antibody Relieves Chronic Low Back Pain

Tanezumab, a monoclonal antibody that inhibits nerve activity, may provide relief to people with chronic low back pain, new research indicates. Chronic low back pain is one of the leading reasons why people seek medical care and the number one cause of disability worldwide. “This demonstration of efficacy is a…Continue readingNerve-blocking Antibody Relieves Chronic Low Back Pain

Air Quality Impacts Early Brain Development

A link between traffic-related air pollution and an increased risk for changes in brain development relevant to neurodevelopmental disorders has been identified by researchers at the University of California, Davis. Their study[1], based on rodent models, agrees with previous epidemiological evidence showing this association. While air pollution has long been…Continue readingAir Quality Impacts Early Brain Development

Neurovascular Function Is Determined By The Neural Metabolic Environment

Blood vessels can sense the metabolic state of neighboring neural cells, recent work in the lab of Asifa Akhtar in Freiburg has shown. The researchers found that the epigenetic regulator MOF is required for equipping neurons with the right metabolic enzymes needed for processing fatty acids. “Something has to tell…Continue readingNeurovascular Function Is Determined By The Neural Metabolic Environment

Memory: How The Brain Constructs Dreams

Our most vivid dreams are a remarkable replication of reality, combining disparate objects, actions and perceptions into a richly detailed hallucinatory experience. How does our brain accomplish this? It has long been suspected that the hippocampus contributes to dreaming, in part due to its close association with memory: according to…Continue readingMemory: How The Brain Constructs Dreams

Alzheimer’s Research: Nilotinib Appears Safe And Affects Biomarkers

A small, phase II, randomized, double blinded, placebo-controlled study to evaluate the impact of low doses of nilotinib in Alzheimer’s disease finds that it is safe and well-tolerated. The researchers, from Georgetown University Medical Center, say the drug should be tested in a larger study to further determine its safety…Continue readingAlzheimer’s Research: Nilotinib Appears Safe And Affects Biomarkers

Blood Plasma Analysis Could Spot Signs Of ALS

Analysis of blood plasma could help identify diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis, according to new research. The work[1] sheds further light on a pathway involved in disease progression and appears to rule out an environmental neurotoxin as playing a role in ALS. “Early diagnosis is important, but…Continue readingBlood Plasma Analysis Could Spot Signs Of ALS

Are Retina Layers Early Warning For Alzheimer’s Disease?

A new imaging device could detect a biomarker of Alzheimer’s disease in the retina, according to research in mice[1]. The device can measure both the thickness and texture of the various layers of the retina at the back of the eye, potentially offering a widespread early warning system for the…Continue readingAre Retina Layers Early Warning For Alzheimer’s Disease?