Smaller Cerebellums Observed in Posttraumatic Stress Disorder

According to new research from a Duke-led brain imaging study, adults with PTSD have smaller cerebellums. The cerebellum, a region of the brain known for dealing with movement and balance, can influence mood and memory, both of which are affected by posttraumatic stress disorder (PTSD). What is unknown is whether a smaller cerebellum predisposes a…

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Somatostatin Neurons Growth Hormone Activity Helps Regulate Anxiety

Growth hormone (GH) operates on various tissues throughout the body, including the bones and muscles. It is also an effective anxiolytic. Researchers from the University of São Paulo (USP) in Brazil recently conducted a study that deepened our understanding of the role of growth hormone in reducing anxiety and, for the first time, identified the…

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Spinal Cord Stimulation Shows Promise for Depression Treatment

Electrical stimulation of the spinal cord is feasible, well-tolerated, and has therapeutic potential for treating depression, according to a pilot clinical trial led by University of Cincinnati researchers at the Lindner Center of HOPE.The research of principal investigator Francisco Romo-Nava, MD, Ph.D., focuses on how the brain-body connection is involved in psychiatric disorders. “We think…

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Cannabis-related Psychiatric Disorders Are On the Rise

The increased potency and pervasive use of cannabis (marijuana) are associated with an increase in cannabis-related psychiatric disorders, according to a new review article published in the New England Journal of Medicine by the University of Maryland School of Medicine (UMSOM). It emphasizes the critical necessity for physicians to promptly identify and manage patients exhibiting…

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Blood Test Detects Suicidal Ideation Biomarkers

In the United States alone, 16.1 million adults suffer from major depression, which costs $210 billion each year. While the major symptoms of depression are psychological in nature, scientists and clinicians have come to realize that depression is a complicated disease with physical consequences throughout the body. Measuring markers of cellular metabolism, for example, has…

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Adolescent Brain Biomarkers May Predict Future Psychological Issues

Researchers describe new methods for precisely locating potential biomarkers in teenage brains that are capable of accurately forecasting cognitive growth and mental health problems. Their new study is the first large-scale analysis of its kind, in which researchers analyzed functional network connectivity (FNC) across scans and identified associations with a variety of health measures in…

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Electroconvulsive Therapy Benefits Stem From Aperiodic Activity Boost

Electroconvulsive therapy (ECT), formerly known as electroshock therapy, involves producing a brief seizure in the brain with regulated doses of electricity. While ECT is extremely helpful for certain mental diseases, particularly depression, the reasons for its effectiveness have long perplexed psychiatrists and neuroscientists. University of California, San Diego researchers may now have the solution. Aperiodic…

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Delayed Sleep Phase Disorder Comorbidities

Delayed sleep phase disorder (DSPD), also known as delayed sleep phase syndrome and delayed sleep-wake phase disorder, is the delay of a person’s circadian rhythm in comparison to societal norms. Elliot D. Weitzman and coworkers from Montefiore Medical Center initially formally identified it in 1981. It is responsible for 7-13% of persistent insomnia complaints. Among…

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Suicide Risk Linked to Brain Inflammation, Loss of Protective Mechanisms

In a first-of-its-kind study, researchers found that lost brain protection systems and overactive inflammation may contribute to the risk of suicide. The results provide additional justification for investigating the potential of anti-inflammatory drugs as a preventive measure, particularly in scenarios of early suicidal ideation detection. “As suicide rates continue to rise, we must develop additional evidence-based strategies…

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