Eukaryotic cells are highly structured objects that make up the majority of life as we know it, including all animals, plants, and fungi. These cells build and maintain their own internal components, such as membrane-bound organelles like nuclei, which store genetic information, or mitochondria, which produce chemical energy. However, much remains unknown about how they…
Tag: Mitochondria
SenP5 Helps Regulate Mitochondrial Dynamics In Brain Development
Mitochondrial dynamics are mainly regulated by dynamin-related protein 1 (Drp1). The molecular mechanisms that affect the functioning of Drp1 influence brain development. But little has been known on how exactly this happens. A recent study1 describes a newly discovered protein in the brain that helps regulate Drp1 and thus, brain function. The finding offers new…
Neuronal Mitochondria Protected From Damage Linked To Alzheimer’s
A new screening platform, developed by scientists at Scripps Research, enables researchers for the first time to rapidly test “libraries” of thousands of molecules to find those that provide broad protection to mitochondria in neurons. Mitochondrial damage is increasingly recognized as a major factor, and in some cases a cause, for diseases of neuronal degeneration…
Mitochondrial Dysfunction Implicated In Alzheimer's Disease
The tragic case of Auguste Deter might have vanished into the recesses of medical history, but for one fact. Her doctor, Alois Alzheimer, made a thorough examination of her medical condition, including her excised brain, discovering the telltale amyloid plaques and neurofibrillary tangles characteristic of her illness. Auguste Deter was the first person diagnosed with…