NGFR Molecule Promotes Early Metastasis In Melanoma

Nerve growth factor receptor (NGFR) drives the process of early metastasis in melanoma, work from an international team of scientists has found. Additionally, blocking the molcule reduces metastasis in animal models. The reduction was achieved using THX-B. This molecule is being tested for the treatment of other pathologies, which will accelerate its possible use in…

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Rova-T Ineffective Against Small Cell Lung Cancer

Rovalpituzumab tesirine (Rova-T) is not effective against small-cell lung cancer (SCLC), four independent studies show. SCLC remains a difficult disease to treat, especially at the time of relapse. Currently, topotecan is among the most effective treatments, but it is not the most desirable and favored drug in the second-line setting because of its toxicity profile.…

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Extravasation Cascade Of Proangiogenic Monocytes To Tumours Detailed

Monocytes after crossing the enflamed endothelial barrier. Credit: University of Geneva

By identifying two cytokines, key factors in the recruitment of blood cells essential to the formation of new blood vessels, and above all, by deciphering how these factors interact simultaneously with blood vessels, researchers at the University of Geneva (UNIGE) have highlighted an additional method of controlling tumour progression. The results suggest that the combined…

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Oleocanthal: the Olive Oil Ingredient that Kills Cancer Cells

An ingredient in extra-virgin olive oil has been found to kill a variety of cancer cells in humans, without harming healthy cells. The ingredient is oleocanthal. A Rutgers University nutritional scientist along with two cancer biologists from New York City’s Hunter College discovered that the compound ruptures a part of the cancerous cell, releasing enzymes…

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