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Predisposition To Hear Voices In Schizophrenia May Be Instituted By Infancy

To investigate the biological origins of hearing “voices” in patients with schizophrenia, a team led by researchers at the Icahn School of Medicine at Mount Sinai used ultra-high field imaging to compare the auditory cortex of schizophrenic patients with healthy individuals. They found that schizophrenic patients who experienced auditory hallucinations had abnormal tonotopic organization of […]

Up To 51% Of Schizophrenia Cases Misdiagnosed Before Reaching Specialty Clinic

About half the people referred to the clinic with a schizophrenia diagnosis didn’t actually have schizophrenia, Johns Hopkins Medicine researchers report in a small study. Therapies can vary widely for people with schizophrenia, bipolar disorder, major depression or other serious types of mental illness, and a misdiagnosis can lead to inappropriate or delayed treatment. The […]

Neurobiological Mechanisms Behind Schizophrenia May Depend On Gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, a new study indicates. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to schizophrenia using neurons derived from induced pluripotent stem cells. Co-ordinated by the University of […]

Gene Expression Rhythms Are Disrupted In Schizophrenia-Affected Brains

Rhythms in gene expression in the brain are highly disrupted in people with schizophrenia, according to a new University of Pittsburgh-led study. The findings also suggest that researchers studying schizophrenia-linked genes in the brain could have missed important clues that would help understand the disease. “Our study shows for the first time that there are […]

Brain Network Structures Can Change Over Time

The connectivity and shape of brain networks — discrete areas of the brain that work together to perform complex cognitive tasks — can alter in fundamental and recurring ways over time, a study led by Georgia State University suggests. The researchers gathered functional magnetic resonance imaging (fMRI) brain imaging data to develop pictures of network […]