schizophrenia

A subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain, report researchers at the RIKEN Center for Brain Science who worked with model mice, postmortem human brains, and people with schizophrenia. Experiments showed that this abnormality likely results from a DNA-modifying reaction during development that lasts throughout life. In addition… Read more

To investigate the biological origins of hearing “voices” in patients with schizophrenia, a team led by researchers at the Icahn School of Medicine at Mount Sinai used ultra-high field imaging to compare the auditory cortex of schizophrenic patients with healthy individuals. They found that schizophrenic patients who experienced auditory hallucinations had abnormal tonotopic organization of… Read more

About half the people referred to the clinic with a schizophrenia diagnosis didn’t actually have schizophrenia, Johns Hopkins Medicine researchers report in a small study. Therapies can vary widely for people with schizophrenia, bipolar disorder, major depression or other serious types of mental illness, and a misdiagnosis can lead to inappropriate or delayed treatment. The… Read more

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, a new study indicates. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to schizophrenia using neurons derived from induced pluripotent stem cells. Co-ordinated by the University of… Read more

Rhythms in gene expression in the brain are highly disrupted in people with schizophrenia, according to a new University of Pittsburgh-led study. The findings also suggest that researchers studying schizophrenia-linked genes in the brain could have missed important clues that would help understand the disease. “Our study shows for the first time that there are… Read more