macrophages

Certain macrophages in the intestines of mice can survive for quite some time, scientists at KU Leuven, Belgium, report. Most importantly, these long-lived macrophages were found to be vital for the survival of the nerve cells of the gastrointestinal tract. This sheds new light on neurodegenerative conditions of the intestine, but also of the brain… Read more

A population of cells called macrophages coat the outer walls of healthy arteries and express a protein called LYVE-1, researchers at National University of Singapore report. The researchers found that when these cells were absent, arteries accumulate collagen and lose their elasticity, becoming stiff and inflexible. Arteries such as the aorta actively transport oxygenated blood… Read more

Abraxane (nab-paclitaxel), a drug created to prevent cancer cells from multiplying has a secondary effect, researchers from NYU Langone Medical Center have discovered. It also switches immune cells that turn down the body’s attack on tumors back into the kind that amplify it. Macrophages – immune cells that home in on tumors – take in… Read more

The body needs a certain amount of inflammation to eliminate invasive organisms and foreign irritants, but too much inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as p62 acts as a… Read more

A molecular regulator that allows salmonella bacteria to switch from actively causing disease to lurking in a chronic but asymptomatic state called a biofilm has been discovered by researchers at the University of Illinois at Chicago. Biofilms cling to surfaces in the body, such as the bronchial tubes or artificial joints, often without causing illness… Read more