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HIV DNA Expelled From The Genomes Of Living Animals

For the first time, scientists have eliminated replication-competent HIV-1 DNA – the virus responsible for AIDS – from the genomes of living animals. The study, a joint effort from researchers at the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC), marks a critical step toward the development […]

Cas12b Enzyme For Eukaryotic Cells Adds To The CRISPR Toolbox

A team that includes the scientist who first harnessed the revolutionary CRISPR-Cas9 and other systems for genome editing of eukaryotic organisms, including animals and plants, has engineered another CRISPR system, called Cas12b. The new system offers improved capabilities and options when compared to CRISPR-Cas9 systems. In a study published in Nature Communications, Feng Zhang and […]

Protein Level DNA Barcoding Identifies Key Cancer Immunity Genes

A new technology for simultaneously analyzing the functions of hundreds of genes with resolution reaching the single cell level has been developed by scientists at Mount Sinai Hospital. The method relies on a barcoding approach using a novel protein. Since the sequencing of the first human genome in the early 2000s revealed a set of […]