vascular biology

Roughly 8.5 million people in the United States suffer from peripheral artery disease (PAD), a narrowing of the arteries in the legs or arms (frequently due to the buildup of fatty plaque) that can cut off blood flow to the limbs, causing tissue death, gangrene, and even amputation. Strategies to combat PAD by delivering compounds… Read more

Scientists have identified a molecule that they say could serve as a fountain of youth for the vascular system. It could also offer a way to turn back the circulatory system’s clock, say researchers. The molecule, which the liver produces during fasting or calorie restriction, can delay vascular aging by preventing senescence — the gradual… Read more

When we have small wounds on our skin or muscles they can usually heal by themselves. But in deeper wounds – such as those in diabetic patients or in muscle tissue after a heart attack – repair is more difficult. These sorts of issues often require more serious treatments, and may eventually need amputation or… Read more

A network of very fine blood vessels that connects bone marrow directly with the blood supply of the periosteum that was previously overlooked has now been discovered by Dr. Anika Grüneboom, a young researcher who is now working at Universitätsklinikum Erlangen. She made this groundbreaking discovery while working on her doctoral thesis at Universität Duisburg-Essen… Read more

β-Hydroxybutyrate, a molecule produced during fasting or calorie restriction has anti-aging effects on the vascular system, which could reduce the occurrence and severity of human diseases related to blood vessels, such as cardiovascular disease, according to a study led by Georgia State University. “As people become older, they are more susceptible to disease, like cancer… Read more