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Link Between Cancer Tumour Growth And Sugar Clarified

The relationship between sugar and cancer has been made clearer by new research from Belgian scientists. The nine-year joint research project, undertaken by Vrije Universiteit Brussel, Katholieke Universiteit Leuven, and the Flanders Institute for Biotechnology, has led to a new understanding of how the Warburg effect, a phenomenon in which cancer cells rapidly break down […]

Breast Cancer Tumor Growth Dependent On Lipid Availability

Breast cancer cells need to take up lipids from the extracellular environment in order to continue proliferating, researchers report in a new study. The main protein involved in this process is LIPG, an enzyme found in the cell membrane (the layer that surrounds a cell) and without which tumor cell growth is arrested. Analyses of […]

Clustered Nanoparticles For Improved Tumor Penetration

Scientists have created a triple-stage “cluster bomb” technique for delivering the chemotherapy drug cisplatin, through nanoparticles designed to break up when they reach a tumor. The particles have not been tested in humans, although similar ways of packaging cisplatin have been in clinical trials. What makes these particles distinctive is that they start out relatively […]

Cancer Stem Cells: How They Thrive When Oxygen Is Scarce

Working with human breast cancer cells and mice, scientists at The Johns Hopkins University say new experiments explain how certain cancer stem cells thrive in low oxygen conditions. Proliferation of such cells, which tend to resist chemotherapy and help tumors spread, are considered a major roadblock to successful cancer treatment. The new research, suggesting that […]

How Recessive Dystrophic Epidermolysis Bullosa Causes Skin Cancer

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55. 80 percent of these patients will die due to metastasis within five years after the cancer has […]