A specific signaling circuit in the brain is deeply involved in motor activity, scientists from the Florida campus of The Scripps Research Institute have found. The new findings that could have an impact the development of therapies for a number of currently untreatable brain disorders such as Parkinson’s and Huntington’s diseases. Despite many advances, the… Read more

Several new biological markers for measuring the progression of Huntington’s disease (HD) have been identified by Stanford University School of Medicine researchers. The findings could help clinical trials that test new treatments for the the inherited neurodegenerative disorder. Although genetic testing can identify HD patients well before the first symptoms appear in middle age, there… Read more

How does cross-talk in brain networks alter when working memory, the mental assembly of information needed to carry out a particular task, is engaged? Scientists at Massachusetts General Hospital have found that dopamine signaling in the cerebral cortex can predict changes in the extent of communication between key brain networks during working memory. Their findings… Read more

The way that dopamine controls the brain’s response to cocaine has been discovered by a Nagoya University-based research team. Findings from this study will reveal new insights into dopamine function in the brain. Researchers have thus far been unable to define how dopamine influences cocaine reward. A recent report published in Neuron has shown that… Read more

Individuals addicted to cocaine may have difficulty in controlling their addiction because of a previously-unknown ‘back door’ into the brain, circumventing their self-control, suggests a new study led by the University of Cambridge. A second study from the team suggests that a drug used to treat paracetamol overdose may be able to help individuals who… Read more