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The Striatum Builds Behavioral Sequences From Sub-second Components

The brain relies on an exquisite balance between the activity of two populations of neurons in a part of the brain called the striatum, the hub for motor and action planning, suggests a new study led by scientists from Harvard Medical School. The findings could help researchers better understand conditions that dramatically impact movement – […]

Psychosis Risk Linked To Impaired Probabilistic Category Learning

Boosting how well people at risk for psychosis learn from positive and negative feedback could potentially keep psychosis at bay, researchers at the University of Missouri have found. The team also found that brain scans using functional magnetic resonance imaging, coupled with behavioral measures, could provide markers for the diagnosis of psychosis risk. Psychotic disorders […]

Cortico-striatal Regulation Of Striatal Activation Is Disrupted In Psychopathy

Psychopath’s brains are wired in a way that leads them to over-value immediate rewards and neglect the future consequences of potentially dangerous or immoral actions, a new study reports. The study relies on brain scans of nearly 50 prison inmates to help explain why psychopaths make poor decisions that often lead to violence or other […]

Intolerance Of Uncertainty Linked To Striatum Grey Matter Volume

Individuals who have trouble coping with uncertainty or the ambiguity of possible future threats may have an unusually large striatum, an area of the brain already associated with general anxiety disorder, according to new research. Lead author Justin Kim, PhD, of Dartmouth College, said: “Uncertainty and ambiguity of potential future threats are central to understanding […]

Striatum Rhesactome Regulates Amphetamine Induced Motor Activity

A specific signaling circuit in the brain is deeply involved in motor activity, scientists from the Florida campus of The Scripps Research Institute have found. The new findings that could have an impact the development of therapies for a number of currently untreatable brain disorders such as Parkinson’s and Huntington’s diseases. Despite many advances, the […]