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Neuron Subpopulation Sustains Breathing Following Spinal Cord Injury

A new study takes lessons from a spinal osteoarthritic condition to identify a neural population that can be used to restore breathing after spinal cord injury. One of the most devastating features of high spinal cord injury is the disruption of the neural circuits that control breathing. Damage to these pathways frequently results in ventilator-dependence, […]

Regenerating Axons Across Complete Spinal Cord Injury

In a collaboration led by EPFL (Ecole polytechnique fédérale de Lausanne) in Switzerland and UCLA (University of California at Los Angeles) in the USA, scientists have now understood the underlying biological mechanisms required for severed nerve fibers to regenerate across complete spinal cord injury, bridging that gap in mice and rats for the first time. […]

Magnetic Kyphoplasty Bone Cement Delivers Targeted Drugs

By adding magnetic particles to surgical cement used to heal spinal fractures, magnetic nanoparticles could be guided directly to lesions near the fractures, researchers at the University of Illinois at Chicago report. Nanoparticles bound to various drugs have been used to target drugs to specific locations or types of cells in the body. Most commonly, […]

Mechanism Underlying Cerebrospinal Fluid Formation Identified

An ion transporter mechanism contributes to the transport of water from the blood into the brain, a new study on mice conducted at the University of Copenhagen reports. If the mechanism could be targeted with medicine, it may prove relevant for treating disorders involving increased intracranial pressure, including brain edema in connection with stroke, and […]