Inordinate activity of an immune system gene linked to schizophrenia reproduces neural and behavioral aspects of the disease in mice, according to a new study by Ashley Comer and Alberto Cruz-Martín of Boston University and colleagues. The finding[1] provides mechanistic support for the importance of the gene in the development of schizophrenia, and may offer… Read more

Being around dogs from an early age may lessen the chance of developing schizophrenia as an adult, according to a study from Johns Hopkins Medicine. And while Fido may help prevent that condition, the jury is still out on whether or not there’s any link, positive or negative, between being raised with Fluffy the cat… Read more

A subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain, report researchers at the RIKEN Center for Brain Science who worked with model mice, postmortem human brains, and people with schizophrenia. Experiments showed that this abnormality likely results from a DNA-modifying reaction during development that lasts throughout life. In addition… Read more

To investigate the biological origins of hearing “voices” in patients with schizophrenia, a team led by researchers at the Icahn School of Medicine at Mount Sinai used ultra-high field imaging to compare the auditory cortex of schizophrenic patients with healthy individuals. They found that schizophrenic patients who experienced auditory hallucinations had abnormal tonotopic organization of… Read more

About half the people referred to the clinic with a schizophrenia diagnosis didn’t actually have schizophrenia, Johns Hopkins Medicine researchers report in a small study. Therapies can vary widely for people with schizophrenia, bipolar disorder, major depression or other serious types of mental illness, and a misdiagnosis can lead to inappropriate or delayed treatment. The… Read more