The connectivity and shape of brain networks — discrete areas of the brain that work together to perform complex cognitive tasks — can alter in fundamental and recurring ways over time, a study led by Georgia State University suggests. The researchers gathered functional magnetic resonance imaging (fMRI) brain imaging data to develop pictures of network [...]

A set of chemical imbalances in the brains of people with schizophrenia related to the chemical glutamate has been elucidated by Johns Hopkins Medicine researchers in recently published studies using animals and people. They have also dicovered how to regulate the levels using a compound derived from broccoli sprouts. The results advance the hope that [...]

Certain combinations of psychiatric medication may be more effective than others in treating patients with schizophrenia, a new study suggests. Combining medications is often referred to as polypharmacy. Antipsychotic drugs are usually the first line of treatment for individuals with schizophrenia. But because these drugs often fail to control symptoms adequately on their own, doctors [...]

People with schizophrenia also have higher levels of antibodies against the Epstein-Barr virus according to new research from Johns Hopkins Medicine and Sheppard Pratt Health System. Epstein-Barr virus (EBV), is a herpes virus that causes infectious mononucleosis, so-called mono. Researchers proposed two explanations for the association of heightened immune responses in patients with schizophrenia and [...]

Epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants have been identified in a study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH). The study details differences in the expression of histone deacetylase (HDAC) enzymes, important regulators of gene [...]