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Tau-mediated RNA Splicing Errors Linked To Alzheimer’s Disease

A novel mechanistic link between alterations in RNA splicing and tau-mediated neurodegeneration in Alzheimer’s disease us reported in a collaborative study in the journal Cell Reports[1]. The study, led by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, integrates data from human brain autopsy […]

STMN2 Gene A Potential Therapeutic Target For ALS

A potential new biomarker and drug target for amyotrophic lateral sclerosis has been identified by research led by stem cell scientists at Harvard University. The study used stem cell models of human motor neurons to reveal the gene STMN2 as a potential therapeutic target, demonstrating the value of this human stem cell model approach in […]