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CrebB: Long-term Memories Are Made Of This

Our brains can store different types of memories. You may have forgotten what you had for lunch yesterday, but still be able to remember a song from your childhood. Short-term memories and long-term memories form via different mechanisms. To establish long-term memories, the brain must produce new proteins, many of which are common to all […]

Chaperone Protein Implicated In Parkinson’s Disease Identified

Lower levels of a chaperone protein might have implications for the development and progression of neurodegenerative diseases such as Parkinson’s disease and Lewy body dementia, new research from the University of Alabama at Birmingham finds. The reduction of chaperone protein 14-3-3 could lead to misfolding and spread of a key brain protein from one brain […]

Endosome pH Imbalance May Contribute To Alzheimer’s Disease

One root of Alzheimer’s disease may be a simple imbalance in acid-alkaline — or pH — chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells, Johns Hopkins Medicine scientists say, after finding new evidence in lab-grown mouse brain cells, called astrocytes. Astrocytes work to clear so-called amyloid beta proteins from the spaces between […]

Phosphoproteomics Uncovers Up To 100 Potential Cancer Drug Targets

A number of proteins that could play a critical role in propagating signals within cells that can lead to uncontrolled cell growth have been uncovered by University of Copenhagen researchers. Uncontrolled cell growth is one of the hallmarks of cancer. The protein researchers, from the Novo Nordisk Foundation Center for Protein Research at the University […]