pharmacokinetics

Gut bacteria may selectively modify the breaking down of a drug, pharmaceutical scientists from the National University of Singapore report in a new study. This causes certain patients to suffer from drug-induced liver injury (DILI), where there are unexpected side effects from consuming a drug, causing liver damage. The discovery and understanding of this process… Read more

The goal of pharmaceutical drug development is to produce compounds that can treat medical conditions effectively without causing side effects (which are known as adverse drug reactions in the pharmaceutical industry). It has been estimated that serious versions of adverse drug reactions occur in over two million patients per year in the US, with 100,000… Read more