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Telomerase-positive Pediatric Brain Tumors: Possible New Treatment Method

An experimental molecular therapy in has been used in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer. The researchers now propose advancing the treatment to clinical testing in children. The small molecule 6-thio-2’deoxyguanosine (6-thio-dG) was tested in brain cancer stem cells derived from tumor cells donated by patients. Researchers also […]

Larotrectinib Shows 93% Response Rate In Pediatric Cancer

Larotrectinib, a first-of-its-kind drug targeting a fused gene found in many types of cancer was effective in 93 percent of pediatric patients tested, researchers at UT Southwestern’s Simmons Cancer Center has announced. Most cancer drugs are targeted to specific organs or locations in the body. Larotrectinib is the first cancer drug to receive FDA breakthrough […]

Growing Pains: Are Growing Pain Symptoms Real?

Growing pains are the most common childhood musculoskeletal condition resulting in frequent visits to healthcare professionals. For two centuries, its incidence, cause and treatment have baffled the health and medical community. There is no single diagnostic test for growing pains. As a result, it continues to be diagnosed more by exclusion than inclusion of symptoms. […]