oncology

The anti-depressant Prozac (Fluoxetine) could be repurposed to take on one of the deadliest childhood tumours and possibly other types of cancer, scientists said. The breakthrough, led by Brunel University London, could spare young patients treatment with highly toxic cocktails of chemotherapy drugs and radiation. “Prozac has the potential to be used in children with… Read more

Lab-grown brain tumor organoids developed from a patient’s own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it, according to a new study. “While we’ve made important strides in glioblastoma research, preclinical and clinical challenges persist, keeping us from getting closer to more effective… Read more

Children who have received radiotherapy for a brain tumor can develop cognitive problems later in life. In their studies on mice[1], researchers at Karolinska Institutet have now shown that the drug lithium can help to reverse the damage caused long after it has occurred. Nowadays, four out of five children with a brain tumor survive… Read more

The process of breast cancer’s spread into the brain involves the “N-methyl-D-aspartate receptor” (NMDAR), which is found on the cell membranes of neurons and is involved in the transmission of nerve impulses, scientists at EPFL’s Swiss Institute for Experimental Cancer Research (ISREC) have discovered[1]. One of the biggest problems with any type of cancer is… Read more

Some cancer cells survive chemotherapy by devouring their neighboring tumor cells, research from Tulane University suggests[1]. This act of cannibalism may give these cancer cells the energy required to stay alive and begin tumor relapse after the treatment is completed. “Understanding the properties of these senescent cancer cells that allow their survival after chemotherapy treatment… Read more