Engineered Nanoparticle Antibody Fragments Destroy Gastric Cancer

illustration of C’ dot nanoparticles adapted with HER2-targeting antibody fragments (dark blue and green) and cancer-killing drugs (teal), entering a tumor cell via HER2 receptors (orange). Credit: Ella Maru Studio

A unique cancer therapy combining antibody fragments with molecularly engineered nanoparticles permanently eradicated gastric cancer in mice, a multi-institutional team of researchers reports. “I’ve seen beautiful results before, but I’ve never seen something that eradicates a tumor like this,” said Dr. Michelle Bradbury, co-lead author and professor of radiology at Weill Cornell Medicine. The “hit…

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