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Obsessive Compulsive Disorder Brains Stuck In A Loop Of Error Processing

The brains of obsessive-compulsive disorder patients get stuck in a loop of “wrongness”, that patients can’t stop even if they know they should, new research suggests. This new analysis of brain scans from hundreds of people with OCD, and people without the condition, was larger than any previous study. It pinpoints the specific brain areas […]

Astrocytes May Contribute To OCD Repetitive Behaviors

UCLA researchers have uncovered some of the basic brain mechanisms behind repetitive behavior, which may ultimately lead to new ways to treat psychiatric disorders, including obsessive compulsive disorder (OCD), at their root. The study was led by Baljit Khakh, professor of physiology and neurobiology at UCLA. Khakh and his team focused on a type of […]

Action-confidence Dissociation Linked With OCD Symptom Severity

People with obsessive-compulsive disorder (OCD) develop an internal, accurate sense of how things work but do not use it to guide behavior, new research from scientists in the UK suggests. The repeated behaviors that characterize obsessive-compulsive disorder are a manifestation of an underlying brain dysfunction that is not yet well understood. “This study shows that […]

Spiny Projection Neurons Show Locally Biased Spatiotemporal Organization

Deep in the brain, in a structure called the striatum, all possible movements that an animal can do are represented in a map of neural activity, new research led by researchers at Columbia University and the Champalimaud Centre for the Unknown has revealed. If we think of neural activity as the coordinates of this map, […]