Having excess body fat, particularly around the gut, may be linked to brain shrinkage, a new study reports. Researchers calculated obesity by measuring body mass index (BMI) and waist-to-hip ratio in their study participants; they found those with higher ratios of both measures had the lowest brain volume. “Existing research has linked brain shrinkage to… Read more

The hormone ghrelin makes us more susceptible to appealing food smells, a phenomenon that encourages overeating and obesity, according to new research. Earlier work by Alain Dagher’s lab at the Montreal Neurological Institute and Hospital of McGill University and colleagues demonstrated that ghrelin encourages eating and the production of dopamine, a neurotransmitter that is important… Read more

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, new research suggests. The study, led by researchers at the Montreal Neurological Institute and Hospital (The Neuro), was an examination of magnetic resonance imaging (MRI) and cognitive test data… Read more

Patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of weight gain than those not taking the drugs, researchers at King’s College London found. They also found that the increased relative risk of weight gain hits its peak after two to three years of continued use… Read more

Researchers have characterized a complex, little-understood receptor type that, when activated, shuts off hunger. The findings may open up opportunities to fight obesity at the cellular level. Jens Meiler, of Vanderbilt University, says pharmaceutical companies have long attempted to develop a small-molecule drug that can do just that. But until now, nobody knew exactly what… Read more