Ghrelin Makes Food Smells Harder To Ignore

The hormone ghrelin makes us more susceptible to appealing food smells, a phenomenon that encourages overeating and obesity, according to new research. Earlier work by Alain Dagher’s lab at the Montreal Neurological Institute and Hospital of McGill University and colleagues demonstrated that ghrelin encourages eating and the production of dopamine,…Continue readingGhrelin Makes Food Smells Harder To Ignore

Genetic Vulnerability To Obesity Is Expressed In The Brain

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, new research suggests. The study, led by researchers at the Montreal Neurological Institute and Hospital (The Neuro), was an examination of magnetic resonance imaging…Continue readingGenetic Vulnerability To Obesity Is Expressed In The Brain

Antidepressant Use Linked To Long-term Weight Gain Risk

Patients prescribed any of the 12 most commonly used antidepressants were 21% more likely to experience an episode of weight gain than those not taking the drugs, researchers at King’s College London found. They also found that the increased relative risk of weight gain hits its peak after two to…Continue readingAntidepressant Use Linked To Long-term Weight Gain Risk

Crystal Structure For Neuropeptide Y Receptor Determined

Researchers have characterized a complex, little-understood receptor type that, when activated, shuts off hunger. The findings may open up opportunities to fight obesity at the cellular level. Jens Meiler, of Vanderbilt University, says pharmaceutical companies have long attempted to develop a small-molecule drug that can do just that. But until…Continue readingCrystal Structure For Neuropeptide Y Receptor Determined

Differences In Muscle Mass May Explain The Obesity Paradox

A new study offers insight into the so-called obesity paradox, a counterintuitive finding that showed people who have been diagnosed with cardiovascular disease live longer if they are overweight or obese compared with people who are normal weight at the time of diagnosis. Obese people live shorter lives and have…Continue readingDifferences In Muscle Mass May Explain The Obesity Paradox

Gut Microbiota Regulates Dietary Fat Digestion And Absorption

Gut microbes facilitate production and secretion of digestive enzymes into the small bowel, according to a new study. The majority of research on the gut microbiome has focused on bacteria in the large intestine, but this study — one of a few to concentrate on microbes in the upper gastrointestinal…Continue readingGut Microbiota Regulates Dietary Fat Digestion And Absorption

How Eating Reduces Hunger Neuron Activity

The biological mechanism behind hunger-driven highs and lows has been detailed by a new study from researchers at the University of Pennsylvania. Although the mere sight or smell of food can temporarily turn off neurons responsible for the drive to eat, they showed that the neurons only stay off if…Continue readingHow Eating Reduces Hunger Neuron Activity