nociception

Notwithstanding the abuse potential of opioid drugs, they have long been the preeminent choice for patients suffering from severe pain. The drugs work by interacting with receptors on brain cells to tamp down the body’s pain response. Neuroscientists at Washington University School of Medicine in St. Louis have now found a way to activate opioid… Read more

People with insomnia and other sleep problems have increased sensitivity to pain, reports a new study. The effect on pain tolerance appears strongest in people who suffer from both insomnia and chronic pain, who may benefit from treatments targeting both conditions. The study, led by Børge Sivertsen, PhD, of the Norwegian Institute of Public Health… Read more

Integrating information across multiple senses aids in selecting an appropriate action. While many examples exist of such synergistic effects, very few studies have identified the neural architecture underlying multisensory convergence. In particular, whether distinct sensory streams converge early, late or at multiple levels in the sensory processing hierarchy was an open question. Now, the entire… Read more