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Tag: neurovascular

Robotic Thread Is Designed To Slip Through The Brain’s Blood Vessels

MIT engineers have developed a magnetically steerable, thread-like robot that can actively glide through narrow, winding pathways, such as the labrynthine vasculature of the brain. In the future, this robotic thread may be paired with existing endovascular technologies, enabling doctors to remotely guide the robot through a patient’s brain vessels to quickly treat blockages and […]

Catalpol Root Extract Gives Neurovascular Protection From Amyloid-Beta Peptides

A research team from Nanjing, China has discovered neuroprotective effects from catalpol, a root extract which has previously been shown to have anti-oxidative properties. The group created a blood-brain barrier in the lab and used amyloid-beta peptide to induce damage before treating the cells with catalpol. They established that catalpol protects brain endothelial cells from […]

Biofabrication Of Brain-Microvessels From Stem Cells & ECM Proteins

A research team from Johns Hopkins University in the USA have recreated human brain-microvessels within the lab. This is important as replicating brain-microvessels and the blood-brain barrier is crucial to studying both healthy function of brain blood vessels and the function and mechanisms of this in disease. Multiple diseases affect the blood vessels of the […]

Simulated Vascular Stiffness Promotes Alzheimer’s Disease Burden In The Lab

Alzheimer’s disease has a complex and faceted set of disease mechanisms. Although it is typically defined as a disease which affects the neurons of the brain, it has become increasingly apparent that the disease also affects the vasculature of the brain in Alzheimer’s progression. The ‘dual hit’ hypothesis suggests that damage to the brains vasculature […]