A fundamentally new method for measuring brain function using a technology known as magnetic resonance elastography (MRE) has been discovered by investigators from Brigham and Women’s Hospital, in collaboration with colleagues at King’s College London and INSERM-Paris. The approach creates maps of tissue stiffness using an MRI scanner. The team has presented data from preclinical… Read more

A molecule has been identified that contributes to painful diabetic neuropathy, an incurable nerve disease that affects about one-quarter of all patients with diabetes, Northwestern University researchers report. Inhibiting the molecule, a chemokine receptor called CXCR4, reversed pain and nerve degeneration in laboratory models and may also provide relief to patients, according to senior author… Read more

A previously undiscovered mechanism of cellular communication, between neurons and immune cells in neuropathic pain, has been revealed in new research from King’s College London. Researchers identified a new method of treating neuropathic pain in mice, which could be more safe and effective than current treatments comprising of opioids and anti-epileptic drugs. Neuropathic pain is… Read more

The molecular basis of chronic nerve pain in diabetes has been pinpointed in a new study from King’s College London. These findings, in a mouse model, could one day lead to treatments which target the source of the pain. Around one in four people with diabetes develop a chronic pain condition induced by nerve damage… Read more

Lyrica is the brand name for a prescription medicine called pregabalin. Although it is an anticonvulsant, or an anti-epileptic drug, pregabalin is commonly prescribed to alleviate nerve or neuropathic pain – a type of pain caused by damage to, or a disease affecting, nerves. Neuropathic pain doesn’t normally respond to common painkillers such as ibuprofen… Read more