New neurons continue to form well into old age, University of Illinois at Chicago researchers examining post-mortem brain tissue from people ages 79 to 99 have found. The study provides evidence that this occurs even in people with cognitive impairment and Alzheimer’s disease, although neurogenesis is significantly reduced in these people compared to older adults… Read more

The ebb and flow of gene expression that may wake neural stem cells from their slumber has been revealed by researchers at Kyoto University studying brain chemistry in mice. The findings may also apply to stem cells elsewhere in the body. “No one before us has directly compared active stem cells in embryos with inactive… Read more

The protein Akna plays a key role in the behavior of neural stem cells, scientists at Helmholtz Zentrum München and Ludwig Maximilian University of Munich (LMU) have discovered. Led by Prof. Dr. Magdalena Götz, director of the Institute for Stem Cell Research (ISF) at Helmholtz Zentrum München and Chair of Physiological Genomics of the LMU… Read more

A novel and unexpected function of nestin, the best known marker of neural stem cells, has been uncovered by researchers at Sahlgrenska Academy at the University of Gothenburg, in collaboration with research groups in Finland, Canada, and Slovenia. In the developing brain, the 3 main cell types, specifically neurons, astrocytes and oligodendrocytes, are generated from… Read more

A non-coding RNA, called Paupar (PAX6 Upstream Antisense RNA), which influences how healthy brains develop during early life, has been identified by scientists from the Universities of Edinburgh, Bath, and Oxford. They have shown that Paupar orchestrates proteins that control neurodevelopment. Since the human genome was first sequenced in 2001, scientists have puzzled over swathes… Read more