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Biofabrication Of Brain-Microvessels From Stem Cells & ECM Proteins

A research team from Johns Hopkins University in the USA have recreated human brain-microvessels within the lab. This is important as replicating brain-microvessels and the blood-brain barrier is crucial to studying both healthy function of brain blood vessels and the function and mechanisms of this in disease. Multiple diseases affect the blood vessels of the […]

Key Role Of Nucleocytoplasmic Transport In ALS

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating adult-onset neurodegenerative disorders. No cure exists for these diseases. Ten percent of ALS patients suffer from a familial form of the disease, while FTD is caused in 40% of patients by a genetic defect. In 2011, the most important genetic cause of ALS and […]

Dance Could Help Treat Neurodegenerative Disorders

Millions of Americans dance, recreationally or professionally. How many of those who ballroom dance, foxtrot, break dance, or line dance realize that they are doing something positive for their brains? “There’s no question, anecdotally at least, that music has a very stimulating effect on physical activity,” said Daniel Tarsy, professor of neurology at Harvard Medical […]

Apigenin Flavonoid In Spices And Herbs Increases Brain Connections

Apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells, Brazilian researchers from D’Or Institute for Research and Education (IDOR), Federal University of Rio de Janeiro (UFRJ) and Federal University of Bahia (UFBA) have shown. Previous experiments with animals had already shown that substances […]

Toxoplasma Gondii Parasite May Alter Brain Signaling

It infects 20 percent of people in the United States, but fortunately, most people who carry the Toxoplasma gondii parasite don’t develop the symptoms of the disease it can cause. Only a small fraction of people, typically with compromised immune systems, develop toxoplasmosis. Toxoplasmosis can lead to abnormal brain function, including seizures, by changing signaling […]