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Alzheimer’s Subtypes Could Affect Future Treatments

A team of neuroscientists at Mayo Clinic in Florida examined a vital region of the brain and found that patterns of Alzheimer’s-related damage differed by subtype and age of onset. The researchers say these observations could have important treatment implications. “Alzheimer’s affects people in different ways. If we learn why it will help us untangle […]

Frontotemporal Dementia Proliferates Via Inter-network Synaptic Connections

Maps of brain connections have been used to predict how brain atrophy would spread in individual patients with frontotemporal dementia (FTD) in a new study[1] from UC San Francisco scientists. The results advance scientists’ knowledge of how neurodegeneration spreads and could lead to new clinical tools to evaluate how well novel treatments slow or block […]

Tau Proteins Spread More Easily In The Aging Brain

Certain molecules involved in Alzheimer’s disease called tau-proteins spread more easily in the aging brain, new research in mice from German investigators suggests. The study was carried out in collaboration with researchers in the US at Harvard Medical School and Massachusetts General Hospital. Alzheimer’s disease usually begins with memory decline and later affects other cognitive […]

Early Role Of Serotonergic Pathology In Parkinson’s Disease Highlighted

The earliest signs of Parkinson’s disease in the brain, many years before patients show any symptoms, have been uncovered by researchers from King’s College London. The results suggest changes to the serotonin system could act as a key early warning signal for the disease. “Parkinson’s disease has traditionally been thought of as occurring due to […]

Viral Protein Corona Linked To Alzheimer’s Amyloid Aggregation

Viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface, new research from Stockholm University and Karolinska Institutet shows. This coat of proteins makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease. “Imagine […]