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Tau Proteins Spread More Easily In The Aging Brain

Certain molecules involved in Alzheimer’s disease called tau-proteins spread more easily in the aging brain, new research in mice from German investigators suggests. The study was carried out in collaboration with researchers in the US at Harvard Medical School and Massachusetts General Hospital. Alzheimer’s disease usually begins with memory decline and later affects other cognitive […]

Early Role Of Serotonergic Pathology In Parkinson’s Disease Highlighted

The earliest signs of Parkinson’s disease in the brain, many years before patients show any symptoms, have been uncovered by researchers from King’s College London. The results suggest changes to the serotonin system could act as a key early warning signal for the disease. “Parkinson’s disease has traditionally been thought of as occurring due to […]

Viral Protein Corona Linked To Alzheimer’s Amyloid Aggregation

Viruses interact with proteins in the biological fluids of their host which results in a layer of proteins on the viral surface, new research from Stockholm University and Karolinska Institutet shows. This coat of proteins makes the virus more infectious and facilitates the formation of plaques characteristic of neurodegenerative diseases such as Alzheimer’s disease. “Imagine […]

Serotonin Regulates Neuronal Mitochondria Biogenesis

A role for the mitochondrial effects of the neurotransmitter serotonin in the facilitation of stress adaptation has been identified in new research. Mitochondria in neurons are the powerhouses that generate energy to execute cellular functions and regulate neuronal survival under conditions of stress. The collaborative research, conducted by Prof. Vidita Vaidya and Prof. Ullas Kolthur-Seetharam […]

Alzheimer’s Disease As A Double-Prion Disorder

Two proteins involved in Alzheimer’s disease pathology act as prions — misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape — new research from UC San Francisco indicates. Using novel laboratory tests, the researchers were able to detect and measure specific, self-propagating prion forms of […]