Molecular Psychiatry

Depression, anxiety, impulsive behavior and poor cognitive performance in children is effected by the amount of sleep they have, report researchers from the University of Warwick. Sleep states are active processes that support reorganization of brain circuitry. This makes sleep especially important for children, whose brains are developing and reorganizing rapidly. “Our findings showed that… Read more

A genome-wide analysis of approximately 200,000 military veterans has revealed six genetic variants linked to anxiety. Some of the variants associated with anxiety had previously been implicated as risk factors for bipolar disorder, post-traumatic stress disorder, and schizophrenia. “This is the richest set of results for the genetic basis of anxiety to date. There has… Read more

Networks within the brain which interact to increase the risk that an individual will think about or attempt suicide have been identified by an international team of researchers. Their review of existing literature[1] underlines how little research has been done into one of the world’s major killers, particularly among the most vulnerable groups. “Imagine having… Read more

During decision-making, neurons in the brain are capable of much more complex processing than previously thought, new research indicates. The findings[1] show that during decision-making, there are a multitude of small sections of dendrite throughout each neuron that process information before it is sent to other neurons. This suggests that much more complex processing can… Read more

Mutations in the gene ANT1 may raise risk for bipolar disorder through a complex interplay between serotonin and mitochondrial signaling in the brain. These two pathways have been separately implicated in bipolar disorder, but the link between levels of the neurotransmitter serotonin and mitochondrial dysfunction had not been established. Researchers at the RIKEN Center for… Read more