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Unique Microglia Cells Linked To OCD And Anxiety

A new lineage of specialized brain cells, called Hoxb8-lineage microglia, has been investigated in a study by University of Utah scientists. They established a link between the lineage and obsessive compulsive disorder and anxiety in mice. “More women than men experience debilitating anxiety at some point in their lives. Scientists want help these people to […]

Choline May Hold Clues To Combatting Alzheimer’s Disease

A lifelong dietary regimen of choline holds the potential to prevent Alzheimer’s disease, a new Arizona State University study[1] suggests. Choline is a safe and easy-to-administer nutrient that is naturally present in some foods and can be used as a dietary supplement. Lead author Ramon Velazquez and his colleagues at the ASU-Banner Neurodegenerative Disease Research […]

Neurogenesis Plays Underappreciated Role In Alzheimer’s Disease

Much of the research on the underlying causes of Alzheimer’s disease focuses on amyloid beta, a protein that accumulates in the brain as the disease progresses. Excess amyloid beta (Aß) proteins form clumps or “plaques” that disrupt communication between brain cells and trigger inflammation, eventually leading to widespread loss of neurons and brain tissue. Aß […]

Autism May Stem from Genetic Defect During Scaffolding Of Developing Brain

A gene mutation associated with autism spectrum disorders normally works to organize the scaffolding of brain cells called radial progenitors necessary for the orderly formation of the brain, report scientists from University of North Carolina at Chapel Hill School of Medicine. The finding sheds light on the molecular details of a key process in brain […]

Alzheimer’s: Microglia Have Key Role In Proliferation Of Tau Pathologies

The link between amyloid beta and tau may lie in the brain’s immune cells that hem in clumps of amyloid, researchers at Washington University School of Medicine in St. Louis have found. If the immune cells falter, amyloid clumps, or plaques, injure nearby neurons and create a toxic environment that accelerates the formation and spread […]