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Combination Of Neural And Vascular Models Produces Neurovascular Tissue Model

Researchers from Keio University (Yokohama, Japan) and Harvard Medical School (Boston, USA) have constructed 3D neurovascular tissues through combining neural and vascular models within a microfluidic system. The researchers built a microfluidic chip with compartments for neural cells and vascular cells, separated by a central portion filled with a specialised 3D biomaterial, called a hydrogel. […]

Human Organ Chip Models Lung Cancer Growth & Drug Response

Human orthotopic lung cancer models have been developed by a team at the Wyss Institute, using two microfluidic devices. For today’s cancer researchers, generating human tumours in mice by injecting cancer cell lines under the skin does not recreate how tumours normally emerge and spread to specific organs in the human body, nor how they […]

Microfluidic Device Enables Less Painful Test For Multiple Myeloma

Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, and the cells can build up in bone marrow, ultimately seeping into the bloodstream. The disease is typically diagnosed through […]

Painless Inexpensive Microneedle System For Drug Monitoring

A new microneedle drug monitoring system that could one day replace costly, invasive blood draws and improve patient comfort has been developed by researchers at the University of British Columbia and the Paul Scherrer Institut (PSI) in Switzerland. The system consists of a small, thin patch that is pressed against a patient’s arm during medical […]

Biofluidics Chip Enables 3D Tissue Biopsies

Biopsies are a gold standard for definitively diagnosing diseases like cancer. Usually, doctors can only take two-dimensional snapshots of the tissue, and they’re limited in their ability to measure the protein levels that might better explain a diagnosis. But now, researchers have developed a new method to acquire three-dimensional atlases of tissue that provide much […]