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Chloroquine Shows Promise For Metastatic Cancer Treatment

Chloroquine, a drug currently used to treat malaria, may be useful in treating patients with metastatic cancers, a new study by University of Kentucky Markey Cancer Center researchers shows. The study found that chloroquine induced the secretion of the tumor suppressor protein Par-4 in both mouse models and in cancer patients in a clinical trial. […]

High Fat Diet Increases Cancer Metastasis

A specific protein called CD36 has been identified on cancer cells which have the ability to metastasize. CD36, found in the cell membranes of tumor cells, is responsible for taking up fatty acids. This unique CD36 activity and dependence on fatty acids distinguishes metastasis-initiating cells from other tumor cells. The team of scientists, headed by […]

How Roaming Breast Cancer Cells Hide In Bone Marrow

A molecular key that breast cancer cells use to invade bone marrow has been identified in mice by scientists at the Duke Cancer Institute. Once inside the marrow, they can be protected from chemotherapy or hormonal therapies that could otherwise eradicate them. Through years of experiments in mice, the scientists have found ways to outmaneuver […]