A distinct group of circulating tumor cells (CTCs) associated with brain metastasis has been detected by Houston Methodist cancer researchers. The finding brings cancer researchers closer to understanding how the “seeds” of metastatic disease can thrive in breast cancer patients and cause it to spread to the brain. Study leader…Continue readingCirculating Tumor Cells Associated With Brain Metastasis
A new stem cell-based method selectively targets and kills cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way. The advance was created by University of California, Irvine scientist Weian Zhao, associate professor of pharmaceutical sciences, and colleagues. They…Continue readingStem Cell Therapy For Cancer Targets Unique Tissue Stiffness
New research links natural and synthetic progestins and the production of specialized cancer cells that act like stem cells in the body. The findings could help scientists target these rare cells that proliferate in breast cancers and metastasize elsewhere, and may help clinicians identify immunotherapies to combat the spread of…Continue readingProgestin Therapy May Cause Enrichment of Cancer Stem Cells
An interaction between two proteins empowers cancer cells to use the physical forces of healthy cells to start spreading to other parts of the body, researchers from the Francis Crick Institute in London and the Institute for Bioengineering of Catalonia (IBEC) in Barcelona have discovered. The process by which cancer…Continue readingHow Cancer Cells Coax Fibroblasts Into Enabling Metastasis
A new bio marker for breast cancer metastasis called Tumor Microenvironment of Metastasis (TMEM) has been found by researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. The density of TMEM was found to be associated with the development of distant organ metastasis via the bloodstream, the most common cause of death from breast cancer. The discovery was published in the journal Clinical Cancer Research March 24, 2009 online edition.
The study may result in the first test to predict the likelihood of breast cancer metastasis via the bloodstream. This is a development that has the possibility of changing the way breast cancer is treated.