Accelerated approval has been granted by the FDA for the checkpoint inhibitor avelumab (brand name Bavencio) for the treatment of patients with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy. Avelumab is the first FDA-approved treatment for metastatic MCC, the first disease that the drug has been approved to treat… Read more

Lorcaserin, a prescription weight-loss pill decreases the urge to use opiates such as oxycodone, researchers have confirmed. Opiate abuse is a major public health problem and according to the U.S. Centers for Disease Control and Prevention, the number of deaths from prescription opiate overdose in America has quadrupled since 1999. High relapse rates, and too… Read more

The novel blood thinner rivaroxaban is more effective at preventing recurrence of life-threatening blood clots in the legs and lungs, and as safe as aspirin, an international research team has found. The results came from the EINSTEIN CHOICE trial – Reduced-dosed Rivaroxaban in the Long-term Prevention of Recurrent Symptomatic VTE (Venous Thromboembolism). The large international… Read more

Researchers have found an association between cardiac arrest and ibuprofen use, as well as another type of non-steroidal anti-inflammatory drug (NSAID) called diclofenac. A cardiac arrest is a serious emergency where the heart stops pumping blood around the body. The Danish study looked at 29,000 people who experienced a cardiac arrest, and then at whether… Read more

Medical media recently reported that a clinicians’ reference handbook had changed advice on how to take the painkiller ibuprofen – commonly sold under the brand names Nurofen and Advil. While the Australian Medicines Handbook previously advised this drug must be taken with food, the updated version says: “Take oral doses with a glass of water… Read more