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Meningeal Lymphatic Dysfunction May Be Factor In Alzheimer’s

Meningeal lymphatic vessels in the brain, newly discovered in 2014, play an essential role in maintaining a healthy homeostasis in aging brains and could be a new target for treatment, new research from a team of neuroscientists and engineers at Virginia Tech and the University of Virginia indicates. The work sheds fresh light on the […]

Meningeal Lymphatic Vessels Uncovered By Brain MRI

The first, long-sought evidence that our brains may drain some waste out through lymphatic vessels, has been observed by researchers at the National Institutes of Health. The finding further suggests the vessels could act as a pipeline between the brain and the immune system. “We literally watched people’s brains drain fluid into these vessels. We […]

Pembrolizumab Gets FDA Approval for Hodgkin Lymphoma Indication

Merck’s therapeutic antibody Pembrolizumab, marketed as Keytruda, has won U.S. Food and Drug Administration approval as a treatment for refractory classical Hodgkin lymphoma. The approval was based on data in 210 patients from the KEYNOTE-087 trial. The clinical trial showed an overall response rate with KEYTRUDA (200 mg every three weeks) of 69 percent (95% […]

Type 2 Innate Lymphocytes Found In Meninges After CNS Injury

A rare form of immune cell has been discovered in the meninges surrounding the brain. The cells may play a critical but previously unappreciated role in battling Alzheimer’s, multiple sclerosis, meningitis and other neurological diseases, in addition to supporting our healthy mental functioning. By using the cells’ power, doctors may be able to develop new […]