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mGlu2 Receptor Involved In Ketamine Antidepressant Response

A receptor called mGlu2 that is critical to the mechanism of fast-acting antidepressants such as ketamine when used to treat depression has been identified[1] by researchers at the University of Maryland School of Medicine (UMSOM). This discovery into how this type of receptor in the brain works with fast-acting antidepressants is a critical discovery in […]

Ketamine Acts Fast To Treat Depression And Its Effects Last — But How?

The molecular mechanisms behind ketamine’s ability to quash depression and keep it at bay are described[1] by researchers led by Mark Rasenick, distinguished professor of physiology and psychiatry in the University of Illinois at Chicago College of Medicine. Two-thirds of participants in clinical studies who did not respond to traditional antidepressants experienced fast and lasting […]

FDA Approves Esketamine For Treatment-resistant Depression

Treatment-resistant depression affects 1 in 3 of the estimated 16.2 million adults in the U.S. who have suffered at least one major depressive episode. For them, two or more therapies have failed and the risk of suicide is much greater. It’s a grim prognosis. There are few therapies for depression that resists treatment, which is […]