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Proinflammatory Cytokines Linked To Chronic Fatigue Syndrome

Chronic fatigue syndrome is associated with variations in 17 immune-system signaling proteins whose concentrations in the blood correlate with the disease’s severity, new research suggests. The findings provide evidence that inflammation is a powerful driver of this mysterious condition, whose underpinnings have eluded researchers for 35 years. The study results could lead to further understanding […]

Tankyrase Signalling Inhibitors Increase Glucose Uptake Into Fat Cells

Researchers have custom built two molecules which bind to and inhibit enzymes called tankyrases that are involved in an important cellular process called Wnt/β-catenin signalling. The research team from Cancer Research at University of Bath, working with colleagues at the University of Oulu in Finland, hope these new molecules could one day become drugs for […]

Cruciferous Vegetables Help Immune System Battle Intestinal Pathogens

Consuming cruciferous vegetables, such as broccoli, kale, cabbage and cauliflower, helps the immune system to fight intestinal pathogens, a recent study in mice shows. The finding could have implications for people with inflammatory bowel diseases. A protein known as the aryl hydrocarbon receptor (AhR) plays a critical role in protecting us from external pollutants, toxins […]

New Inflammatory Marker Genome Links Identified

New links between the human genome and inflammation tracers have been found by researchers in Finland. In a study of over ten million DNA variations, new possibilities for treatment of diseases such as multiple sclerosis, Crohn’s disease and celiac disease were uncovered. Researchers at the Research Centre of Applied and Preventive Cardiovascular Medicine at the […]

Otulipenia: Early-onset Autoinflammatory Disease Discovered

A rare and sometimes lethal inflammatory disease called otulipenia, primarily affecting young children, has been discovered by researchers at the National Institutes of Health. They have also identified anti-inflammatory treatments that ease some of the patients’ symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive. Otulipenia is caused by the […]