immunology

That weary feeling that sets in with an illness is an emotion that helps you fight off infection, a University of Oregon research team reports. Slack facial muscles and drooping eyelids appear early. Exhaustion, loss of appetite, and increased sensitivity to cold and pain come on. Those signs are among a long list of features… Read more

Differences in the genes of the immune system sculpt the assortment of bacteria that colonize the digestive system, new research[1] by scientists at the University of Chicago indicates. “When the input is standardized, you can compare mice of different genetic strains and see what these genetics do to the microbiome in recipient mice. This approach… Read more

It is now achievable to train a transplant recipient’s immune system to accept transplanted cells and organs without the long-term use of anti-rejection drugs, scientists at University of Minnesota have shown. In a pre-clinical study, researchers at the University of Minnesota Medical School‘s Department of Surgery and Schulze Diabetes Institute, collaborating with colleagues at Northwestern… Read more

Roughly 8.5 million people in the United States suffer from peripheral artery disease (PAD), a narrowing of the arteries in the legs or arms (frequently due to the buildup of fatty plaque) that can cut off blood flow to the limbs, causing tissue death, gangrene, and even amputation. Strategies to combat PAD by delivering compounds… Read more

Researchers report identifying the “fingerprint” of the immune cells that characterize multiple sclerosis. The discovery could lead to new ways to monitor and treat the disease. “We identified a specific population of white blood cells augmented in the peripheral blood of MS patients that have two properties characteristic of MS: They can move from the… Read more