A new technique to analyze biochemical changes unique to Huntington’s disease has been developed by researchers at the universities of Southampton and Cambridge. The breakthrough[1] has the potential to lead to the improved diagnosis of disease onset and possibly better ways to track the effects of new treatments. Huntington’s disease damages nerve cells in the… Read more

Alterations in the connectivity of cerebral white matter associated with the diverse nature of apathy in Huntington’s disease have been identified by researchers[1]. The finding suggest a potential use of this syndrome as a biomarker of disease progression, and may lead to personalized treatments for apathy as a multidimensional syndrome in other neurodegenerative disorders. “Our… Read more

The build-up of urea in the brain to toxic levels can cause brain damage, and eventually dementia, an international team of scientists has discovered. The finding, of a major cause of dementia, has important implications for possible treatment and diagnosis. The work follows on from earlier studies, led by professor Garth Cooper from The University… Read more

A gene variant that influences whether Huntington’s disease breaks out earlier or later than expected has been discovered. The findings could contribute to improved diagnosis and disease-modifying therapies. Huntington’s disease is an inherited and progressive neurodegenerative disease. A typical symptom is involuntary movements. While the symptom normally debuts in middle-age, there is wide individual variation… Read more

Significant vascular changes in the brains of people with Huntington’s disease have been identified in an international study led by researchers from Université Laval and CHU de Québec-Université Laval The breakthrough will have significant implications for our understanding of the disease and could be the key to new therapeutic targets for treating this fatal neurodegenerative… Read more