When feelings of hunger occur, we typically interpret them as a cue to reach for a snack. When we start to feel full, we take it as a sign that we should stop eating. New research, however, shows that these associations can be learned the other way around, such that satiation becomes a cue to… Read more

MIT neuroscientists have discovered that brain cells called glial cells play a critical role in controlling appetite and feeding behavior. In a study of mice, the researchers found that activating these cells stimulates overeating, and that when the cells are suppressed, appetite is also suppressed. The findings could offer scientists a new target for developing… Read more

Neurons in the brain that control hunger are regulated by AMPK (5′ AMP-activated protein kinase), a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School. High AMPK activity levels significantly increase the firing of “hunger” neurons known as AgRP neurons, leading to greater… Read more

A brain circuit that not only promotes fullness in hungry mice, but also removes the almost painful sensation of grating hunger, has been discovered by a team of researchers. The findings that could provide a promising new target for the development of weight-loss drugs. Anyone who has ever tried to lose weight knows that it’s… Read more