New evidence that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor progression, has been found by scientists at Baylor College of Medicine. The findings[1] show that several variants of the PIK3CA gene drive tumor progression and that two variants in… Read more

The process of breast cancer’s spread into the brain involves the “N-methyl-D-aspartate receptor” (NMDAR), which is found on the cell membranes of neurons and is involved in the transmission of nerve impulses, scientists at EPFL’s Swiss Institute for Experimental Cancer Research (ISREC) have discovered[1]. One of the biggest problems with any type of cancer is… Read more

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with a vengeance to then turn deadly. Researchers at Cincinnati Children’s Hospital Medical Center used a powerful new computer-assisted technology… Read more

A computer-assisted diagnostic procedure helps physicians detect the growth of low-grade brain tumors earlier and at smaller volumes than visual comparison alone, according to a new study by Hassan Fathallah-Shaykh of the University of Alabama at Birmingham, and colleagues. Additional clinical studies are needed to determine whether early therapeutic interventions enabled by early tumor growth… Read more

A molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer glioblastoma has been uncovered by scientists, using cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer. The study identified a subpopulation of cells critical to glioblastoma formation – the early primitive progenitor cells of oligodendrocyte brain… Read more