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Tag: Glioblastoma

Olfactory Cells May Act As Glioma Gene Therapy Trojan Horse

A specific type of cell essential to the ability of olfactory neurons to regenerate may be genetically engineered to deliver anticancer therapy to the dangerous brain tumors called glioblastomas, researchers from Massachusetts General Hospital (MGH) report. The team used olfactory ensheathing cells to deliver an anticancer agent only to tumor cells and how the treatment […]

TERT Promoter Mutation Is Key To Glioblastoma’s ‘Immortality’

Patient-derived glioblastoma cells with telomerase reverse transcriptase (TERT) promoter mutations depend on a particular form of a protein called GABP for their survival, UC San Francisco researchers have discovered. The finding reveals how a mutation in the gene regulator – the third most common mutation among all human cancers and the most common mutation in […]