glial cells

An immune signal named interleukin 33 (IL-33) plays a crucial role in allowing the brain to maintain the optimal number of synapses during the development of the central nervous system (CNS), indicates a study from University of California, San Francisco. Between the ages of two and four, the human brain has an estimated one quadrillion [...]

AKT, a kinase regulating numerous cellular processes in the brain, comes in three distinct varieties residing in different kinds of brain cells, and affecting brain health in very distinct ways, new research from University of Colorado at Boulder has found. The discovery could lead to new, more targeted treatments for everything from glioblastoma to Alzheimer’s [...]

Neurally implanted devices transmit targeted electrical stimulation to the nervous system, to modify abnormal brain activity. It is usually assumed that neurons are the only important brain cells that need to be stimulated by these devices. But new research suggests that it could also be important to target the supportive glial cells surrounding the neurons. [...]

Glia, a collection of non-neuronal cells that had long been regarded as passive support cells, in fact are vital to nerve-cell development in the brain, a team of biologists has revealed. The finding offers new insights into the building of the nervous system. “The results lead us to revise the often neuro-centric view of brain [...]

A new signaling pathway that directly connects two major receptors in the brain associated with learning and memory has been discovered by neuroscientists at Tufts University School of Medicine. The connection, between the N-methyl-D-aspartate receptor (NMDAR) and the alpha 7 nicotinic acetylcholine receptor (a7nAChR), has significance for current efforts to develop drugs to treat schizophrenia. [...]