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Gliotransmitter ACBP Plays Key Role In Obesity

The acyl-CoA-binding protein, or ACBP, has a direct influence on the neurons that allow rodents and humans to maintain a healthy weight, researchers from the University of Montreal Hospital Research Centre (CRCHUM) have shown for the first time in mice. In April 2015, Thierry Alquier, a CRCHUM researcher and the lead author of this study, […]

Neuron-glia Trans Signaling Intervention Mediates Neurotoxicity In Parkinson’s Model

A new framework for understanding the pathology of Parkinson’s disease is provided by research from the Buck Institute for Research on Aging. Working in two fruit fly models of Parkinson’s, researchers at the Buck Institute elucidated a novel molecular mechanism that orchestrates a harmful cascade of inflammatory signaling and demonstrated that its disruption protects neurons […]

Genetic Mechanisms Steering The Trajectory Of Astrogliogenesis

New findings that may help pinpoint what goes awry with glia in neurodegeneration have been produced by a research team led by Professor Benedikt Berninger of the Institute of Physiological Chemistry at the Mainz University Medical Center. Two types of cells are active in the brain: nerve cells and glial cells. The latter have long […]

Fibromyalgia Patients Show Elevated Brain Glial Activation

Widespread inflammation in the brains of patients with the poorly understood condition called fibromyalgia has now been documented for the first time. Characterized by symptoms including chronic widespread pain, sleep problems, fatigue, and problems with thinking and memory, fibromyalgia affects around 4 million adults in the U.S., according to the Centers for Disease Control and […]