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Genomic Mismatch May Explain Why Some Kidney Transplants Fail

A genomic incompatibility could explain why many kidney transplants fail, even when donors and recipients are thought to be well-matched, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons suggests. The genomic collision is a genetic incompatibility between kidney donor and recipient, causing the recipient to mount an immune attack […]

Neuroscientists Identify Gene Networks Tied To Dementia

A UCLA-led research team has pinpointed genetic processes involved in the neurodegeneration that occurs in dementia. This represents an important step on the path toward developing therapies that could slow or halt the course of the disease. The researchers discovered two major groups of genes involved in mutations that result in an overproduction of a […]

DNA Sequencing Is Inadvertantly Exacerbating Social Biases And Inequalities

At the cutting edge of modern science, DNA sequencing promises to transform many aspects of human life. It’s already playing a significant role in law enforcement, as well as medical and historical research. But there’s a growing inequality in its impacts and in the chances of your genetic data being recorded – whether that’s by […]

How Big Data Is Changing Science

“This is when I start feeling my age,” says Anne Corcoran. She’s a scientist at the Babraham Institute, a human biology research centre in Cambridge, UK. Corcoran leads a group that looks at how our genomes – the DNA coiled in almost every cell in our bodies – relate to our immune systems, and specifically […]