gene expression

Rhythms in gene expression in the brain are highly disrupted in people with schizophrenia, according to a new University of Pittsburgh-led study. The findings also suggest that researchers studying schizophrenia-linked genes in the brain could have missed important clues that would help understand the disease. “Our study shows for the first time that there are… Read more

In recent years, MIT scientists have developed a new model for how key genes are controlled that suggests the cellular machinery that transcribes DNA into RNA forms specialized droplets called condensates. These droplets occur only at certain sites on the genome, helping to determine which genes are expressed in different types of cells. In a… Read more

A genomic mechanism by which a finite number of genes can ultimately help distinguish a seemingly near-infinite number of scents has been identified by researchers from Columbia University. The human nose can distinguish one trillion different scents – an extraordinary feat that requires 10 million specialized nerve cells, or neurons, in the nose, and a… Read more

Differences in the cells that give skin its resilience and strength during wound repair may explain why individuals heal differently, according to a new Yale study. Fibroblasts, the cells that form the protein structure beneath the surface of the skin, were once thought to be fairly uniform in their function. However, the new study found… Read more

A genetic network linked to autism has been uncovered by researchers at the University of Toronto, The findings will facilitate developing new therapies for this common neurological disorder. As part of a collaborative research program focusing on autism led by Benjamin Blencowe, a professor in the University of Toronto’s Donnelly Centre for Cellular and Biomolecular… Read more