gene editing

The gene editing tool known as CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) enables permanent modification of genes within living organisms has been in existence only for a few years. But already, scientists are coming up with novel offshoot applications of the breakthrough technology. Now, a CRISPR protein that targets RNA has been adapted by… Read more

A new method lets researchers quickly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine’s understanding of the genetically inherited risks of developing heart disease, diabetes, cancer, neurological disorders, and others, and lead to new treatments. Charles Gersbach… Read more

Scientists at California Institute of Technology have modified cells of the lower-body region into facial tissue that makes cartilage, in new experiments with bird embryos. The researchers discovered a “gene circuit,” composed of just three genes, that can alter the fate of neural crest cells destined for the lower bodies of birds, turning them instead… Read more

Researchers from MIT and the Broad Institute of MIT and Harvard, as well as the National Institutes of Health, Rutgers University at New Brunswick, and the Skolkovo Institute of Science and Technology, have characterized a new CRISPR system that targets RNA, rather than DNA. The new approach has the potential to open a powerful avenue… Read more

CRISPR/Cas9 has gained attention among basic research scientists for it’s ability to quickly edit the genomes of a diverse range of model organisms. Now, University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9. Typically, CRISPR involved a time-consuming bottleneck when creating knockout mice… Read more