Genetically Modified Humans Are Possible, But Do We Really Want Them?

We are entering a new era as a species. For the first time, we are not only able to read our genetic code but also edit it. This will revolutionise our ability to treat disease and it will improve the lives of millions if not billions of people. But it…Continue readingGenetically Modified Humans Are Possible, But Do We Really Want Them?

Cas12b Enzyme For Eukaryotic Cells Adds To The CRISPR Toolbox

A team that includes the scientist who first harnessed the revolutionary CRISPR-Cas9 and other systems for genome editing of eukaryotic organisms, including animals and plants, has engineered another CRISPR system, called Cas12b. The new system offers improved capabilities and options when compared to CRISPR-Cas9 systems. In a study published in…Continue readingCas12b Enzyme For Eukaryotic Cells Adds To The CRISPR Toolbox

New Viral-mediated Strategy for Genome Editing In The Brain

A new tool that, for the first time, allows precise genome editing in mature neurons, has been developed by researchers at the Max Planck Florida Institute for Neuroscience (MPFI). Genome editing technologies have revolutionized biomedical science, providing a fast and easy way to modify genes. However, the technique allowing scientists…Continue readingNew Viral-mediated Strategy for Genome Editing In The Brain

Retinitis Pigmentosa: Restoring Visual Function With CRISPR/Cas9

Mutated optic rod photoreceptors have been reprogrammed, using the gene-editing tool CRISPR/Cas9, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa. The study was done by researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health,…Continue readingRetinitis Pigmentosa: Restoring Visual Function With CRISPR/Cas9

Genetic Circuits Target Cells For Boolean Logic And Arithmetic

A new platform offers a fast and more efficient way to target and program mammalian cells as genetic circuits, even complex ones. Wilson Wong, professor of biomedical engineering at Boston University, explains: “The problem synthetic biologists are trying to solve is how we ask cells to make decisions and try…Continue readingGenetic Circuits Target Cells For Boolean Logic And Arithmetic

Novel CRISPR Tool Rapidly Detects Viruses And Bacteria

The gene editing tool known as CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) enables permanent modification of genes within living organisms has been in existence only for a few years. But already, scientists are coming up with novel offshoot applications of the breakthrough technology. Now, a CRISPR protein that targets…Continue readingNovel CRISPR Tool Rapidly Detects Viruses And Bacteria

New Method Screens DNA For Non-protein-coding Regulatory Elements

A new method lets researchers quickly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine’s understanding of the genetically inherited risks of developing heart disease, diabetes, cancer, neurological disorders, and others, and lead…Continue readingNew Method Screens DNA For Non-protein-coding Regulatory Elements