A lone gene mutation that causes an inherited form of frontotemporal dementia makes it harder for neurons in the brain to communicate with one another, leading to neurodegeneration, an international team of researchers, led by Washington University School of Medicine in St. Louis, has found. Unlike the more common Alzheimer’s disease, frontotemporal dementia tends to… Read more

A new type of human brain cell that has never been seen in mice and other well-studied laboratory animals has been identified by researchers. The research team, co-led by Ed Lein, Ph.D., Investigator at the Allen Institute for Brain Science and Gábor Tamás, Ph.D., a neuroscientist at the University of Szeged, dubbed these new cells… Read more

Dorsal raphe serotonin and GABA neurons receive biased input from the same regions, new research from Stanford University suggests. As Liqun Luo was writing his introductory textbook on neuroscience in 2012, he found himself in a quandary. He needed to include a section about a vital system in the brain controlled by the chemical messenger… Read more

Survival of neurons in mice depends on the activity of pyramidal cells in a critical window of postnatal development, a new study from King’s College London researchers indicates. The finding represents a fundamental process by which brains are built, and may have profound implications for understanding neurodevelopmental conditions like autism and epilepsy. The study also… Read more

Evidence suggesting emotional stress in infancy has significant and far-reaching effects on the body, and could result in disease later in life, has been found. Psychological stress in infancy dramatically changes the amount of an important class of proteins, called GABAA receptors, which in turn may alter the workings of the heart, lungs, kidneys and… Read more