fragile x

The absence of a protein called fragile X mental retardation protein (FMRP) can unbalance critical molecular processes within adult brain cells and lead to the neural and cognitive changes seen in fragile X syndrome, researchers at the University of Wisconsin–Madison report. Using animal models and chemical compounds, the researchers also showed that rebalancing the molecular… Read more

Babies with the neurodevelopmental condition fragile X syndrome had less-developed white matter compared to infants that did not develop the condition, an imaging study from UNC School of Medicine researchers indicates. The work shows that there are brain differences related to the neurodevelopmental disorder established well before a diagnosis is typically made at age three… Read more

A previously undetected link between the gene that causes fragile X syndrome and increased tissue growth has been found by researchers at Indiana University. The finding could uncover a key biological mechanism behind the serious physical and mental impairments caused by the disorder. Fragile X syndrome is in inheritable genetic condition that is estimated to… Read more

Two proteins associated with fragile X play a key role in the proper development of neurons in mice, a new study shows. The study also showed that although the two proteins act through distinct mechanisms in the formation of new neurons, they also share some duties. According to co-author and Waisman Center and Department of… Read more