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Trojan Horse Chemotherapeutics Disguise Themselves As Fat

A new stealth drug-delivery method that disguises anti-cancer drugs as fat in order to outsmart, penetrate and destroy tumors has been developed by scientists. Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth. The drug also is lower in toxicity than current chemotherapy […]

Synthetic Metal–Organic Molecular Knots Potential New Anti-Cancer Category

The biological activity of five new, metal-organic hybrid knotted molecules, termed metal-organic trefoil knots (M-TKs), has been developed and studied by researchers from NYU Abu Dhabi (NYUAD). These molecules can effectively deliver metals to cancer cells, demonstrating the potential to act as a new category of anti-cancer agents. These nanoscale, water-soluble M-TKs showed high potency […]

Chemically Reprogramming Human Astrocytes Into Neurons

A set of four, or even three, molecules that could convert glial cells into new neurons has been identified by researchers at Pennsylvania State University. The simple drug cocktail could potentially be used to treat stroke, Alzheimer’s disease, and brain injuries. “The biggest problem for brain repair is that neurons don’t regenerate after brain damage, […]

Inhalable Form Of Messenger RNA Created

Messenger RNA, which can induce cells to produce therapeutic proteins, holds great promise for treating a variety of diseases. The biggest obstacle to this approach so far has been finding safe and efficient ways to deliver mRNA molecules to the target cells. In an advance that could lead to new treatments for lung disease, MIT […]