A unique pattern of DNA damage that arises in brain cells derived from individuals with a macrocephalic form of autism spectrum disorder (ASD) has been uncovered by researchers at the Salk Institute. The finding helps explain what might go awry in the brain during cell division and development to cause the disorder. “Division, or replication… Read more

A new imaging technology could allow scientists to look inside cells and watch dozens of different molecules in action at once, by labeling them with short strands of  barcoded DNA that blink on and off with their own unique rhythm. When attached to cells or other objects and observed for enough time, these barcodes could… Read more

Researchers at Bar-Ilan University in Israel report a novel and unexpected function of sleep that they believe could explain how sleep and sleep disturbances affect brain performance, aging and various brain disorders. Using 3-D time-lapse imaging techniques in live zebrafish, the researchers were able to define sleep in single-chromosome resolution, and show for the first… Read more

At the cutting edge of modern science, DNA sequencing promises to transform many aspects of human life. It’s already playing a significant role in law enforcement, as well as medical and historical research. But there’s a growing inequality in its impacts and in the chances of your genetic data being recorded – whether that’s by… Read more

A new technology for simultaneously analyzing the functions of hundreds of genes with resolution reaching the single cell level has been developed by scientists at Mount Sinai Hospital. The method relies on a barcoding approach using a novel protein. Since the sequencing of the first human genome in the early 2000s revealed a set of… Read more